Treehouse Mid-year Research Updates

It’s time to share Treehouse’s mid-year research updates! We’re bringing you research highlights from 2021 publications.

Kicking it off, our colleague Holly Beale recommends reporting a dataset’s sequencing depth in mapped, exonic, non-duplicate (MEND) reads, which definitively inform the reproducibility of gene expression. Further, Holly and team offer up the tools and script to do so. Click through for the links.  https://academic.oup.com/gigascience/article/10/3/giab011/6169410

Next up in Treehouse’s mid-year research update series, we bring you a study from our colleagues Lauren Sanders & Allison Cheney on diffuse midline gliomas with histone H3 K27M (H3K27M) mutations. 

This study analyzed multiple, publicly available RNA sequencing datasets. It’s a great example of how we can gain insight through combined analysis of previously published datasets, which highlights the importance of ensuring genomic data is freely available. ​​https://academic.oup.com/gigascience/article/9/12/giaa136/6034793